Skin Allergy Vaccination

Recently, the epicutaneous allergen administration is presented as a novel method of allergen-specific immunotherapy. This novel method based on Blamoutier and his coworkes, they applied in contrast to SCIT the allergen drops onto heavily scarified skin. “On the proximal volar aspect of the lower arm, in a square area of 4×4 cm, chessboard-like horizontal and vertical scratches are made with a needle. These scratches should be superficial and not cause bleeding”. Consistently, allergic side effects were observed only rarely when allergen was applied via the skin, and if they occurred nevertheless, these reactions were always milder than under conventional SCIT.

These promising results were supported by several studies performed in the subsequent years all over Europe, from Switzerland to Portugal. Overall, symptom relief was obtained rapidly and allowed for co-seasonal treatment. The reported treatment success rates of 80 % exceeded the success rates under conventional SCIT.

Instead of scratching the skin with a lancet the P.L.E.A.S.E.® device is used to create micropores in the skin. This treatment is a good option where no allergy therapy product is available, eg. mould, fungus, ...

Positive experience for the patient



   Needle free

   No scars with microporation

Positive experience for the doctor


   Easy to use

   Reliable automated procedure

   Fast procedure

   No blooding

   No sharp waste