Aesthetic dermatology

Novel, compact fractional aesthetic platform

A vast amount of topical or invasive (applied through needle ) bio-active agents are used in aesthetic dermatology. The protective properties of the skin often diminish the efficiency, or demand an invasive and thus, painful and non-homogenous delivery. SMART PORATION™ Therapy using the P.L.E.A.S.E.® Professional device allows to deliver these substance in a more even, painless and especially very efficient manner.


Pantec Biosolutions currently evaluates several applications where micro-poration of the skin can be used to deliver certain drugs or cosmeceuticals to the right skin layer.


SMART PORATION™ Therapy is a novel approach to increase efficiency by decreasing total treatment time, pain and side effects.

The process starts by using the P.L.E.A.S.E.® Professional device for controlled micro-poration of the skin. Pre-stored parameters allow the creation of pores, which have the right depth for the designated bio-active agent; and the desired density for the prescribed dosage. Now, the drug or bio-active agent or active-ingredient cosmeceutical will be applied on the treated area. The treating physician will determine the right agent based on the patient’s condition (personalized medicine). The final step may include the occlusion of the treatment zone, which can last for hours but also days.

Currently available bio-active substances can be used to perform SMART PORATION™; but Pantec Biosolutions partners with pharmaceutical corporations to market specific agents.


P.L.E.A.S.E.® Professional is appropriate for use in a full range of applications currently addressed by dermatologic or aesthetic medicine treatments::


Please visit P.L.E.A.S.E.® Professional for further information.