P.L.E.A.S.E.® Home: the revolution of transdermal drug deliveryThe P.L.E.A.S.E.® - device is the most convenient, safe and user-friendly "handheld" to pretreat the skin painlessly prior to intraepidermal drug delivery.
Due to its design and simple user interface, the P.L.E.A.S.E.® - device can be applied equally by patients and medical personnel without special training.
Method of use
- The device including a disposable tip is gently pressed to the intraepidermal application site (e.g. the inner forearm)
- The poration process is started by pressing a button upon proper skin contact.
- Prior to the poration process the physician or other authorised medical personnel sets the poration parameters necessary for the therapeutic dose of the intraepidermal system ("drug patch").
- The actual poration process can take from 1 to 5 seconds depending on the drug dose to be applied.
- Immediately after the poration process is finished the poration area will be covered with the drug patch system.
- The drug then diffuses easily through the dermis where it can be absorbed by the blood system.
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