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P.L.E.A.S.E.® |
| Schematic |
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| Method |
Laser ablation |
| Painfree method |
Very short laser pulses |
Eliminate thermal damage in the tissue surrounding pore => proved by clinical study |
| Pore Ø |
≈ 200 µm |
Much wider pores than competition => more diffusion => more drug can permeate into the system |
| Pore depth |
≈ 20 - 150 µm
In process control
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Adapt to different skin thickness and finetuning of dose => higher therapy success rate |
| Pore number |
1 - 5000 per pore array; dose control
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Extremely flexible dosing with regard to different therapies => large mg amounts of drug can permeate => variable dosage with one patch |
| Treatment area |
Up to 5 cm2 |
Greater treatment area than competition => more pores per area possible => more drug can permeate into the system |
| Opened area (diffusion area) |
20 - 300 mm2
Dose control
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100 x more diffusion area than competition => more drug can permeate into the system => more therapies accessible by the P.L.E.A.S.E.® |
