Due to its precise micropore control, P.L.E.A.S.E.® is ideal for allergy vaccine delivery. In collaboration with Biomay AG, an established mouse model of allergic asthma (recombinant grass pollen) was used to show proof of concept of epidermal recombinant grass pollen delivery.
Subcutaneous immunotherapy (SCIT) is a common practice to desensitise patients against allergens contained in e.g. dust mites, grass and tree pollen, dog hair, cat hair. A series of injections are administered to the patient over many months in order to achieve immunisation.
In recent years, sublingual immunotherapy (SLIT) has become an alternative treatment option.
Both treatment options have limitations with regard to convenience (painful injections), side effects and efficacy. Based on first animal data , P.L.E.A.S.E. IT (Immunotherapy) may represent an advantageous therapy option.
